INTRODUCTION Systematic measurement of population physical activity levels is an important component of public health surveillance.

OBJECTIVES Describe patterns of physical activity in the Cuban population aged 15–69 years and identify factors associated with regular physical activity.

METHODS A descriptive cross-sectional study was conducted using a complex sampling design, representative of urban and rural areas, sex and age groups, including 7915 individuals. The International Physical Activity Questionnaire (short format) was applied. The population was classified as active, irregularly active and sedentary, according to sex, age, marital status, education, skin color, employment and perception of health risk related to physical inactivity or overweight. Percentages, odds ratios (OR) and 95% confidence intervals (CI) were calculated and a multinomial regression model was fitted with active persons as the reference category.

RESULTS Approximately 71% of the population self-classified as active, 23% as sedentary and 5.9% as irregularly active. Women had a higher probability of being sedentary (OR 2.51, CI 2.12–2.98) and irregularly active (OR 2.56, CI 95% 1.87–3.49). The probability of being sedentary increased with age (OR 1.19, CI 1.12–1.26), and also with the condition of being a homemaker, retired, or unemployed. Perceiving overweight as a high risk to health reduced likelihood of inactivity (OR 0.49, CI 0.29–0.83).

CONCLUSIONS Some 7 of 10 Cubans are physically active. The groups with the highest probability of inactivity and irregular activity and associated factors have been identified through national application (for the first time) of the International Physical Activity Questionnaire. The results should be taken into account for implementation of specialized strategies to promote systematic physical activity.

KEYWORDS Physical activity, physical exercise, sedentary lifestyle, health behavior, risk factors, chronic disease, women’s health, surveillance, Cuba

INTRODUCTION Shifts in diabetes onset to earlier ages, globally and in Cuba, signify greater risk of early complications and premature death, with consequent economic and social repercussions for families and health systems.

OBJECTIVE Describe the trend in diabetes burden in Cuban children and adolescents in the period 1990 to 2010, in terms of disability-adjusted life years.

METHODS A descriptive epidemiological study was conducted of diabetes burden in Cuba, analyzing the years 1990, 1995, 2000, 2005 and 2010 for the age group 0–19 years. Disability-adjusted life years were obtained from the sum of potential years of life lost plus years lived with disability. The first is calculated based on total deaths in the country in which diabetes was recorded as underlying cause; the second from the product of severity, as assigned to diabetes in similar studies, and incidence and average duration, provided by the DISMOD II program, which estimates six internally consistent epidemiological indicators.

RESULTS Mortality indicators improved, with a decrease in the rate of potential years of life lost in boys from 21.9/100,000 population in 1990 to 0 in 2010, and in girls from 38.8/100,000 in 1990 to 4.9/100,000 in 2010 (1% of disability-adjusted life years in girls in 2010, corresponding to one death). In contrast, years lived with disability increased by 134.5% in boys and 156.4% in girls. The net result was that disability-adjusted life years increased by >100% in both sexes (from 137.2 to 321.9/100,000 in boys and from 157.3 to 403.3/100,000 in girls, increases of 102.3% and 108.1%, respectively).

CONCLUSIONS Disability-adjusted life years lost for diabetes in Cuban children and adolescents have increased, due to disability, while mortality has decreased.

KEYWORDS Diabetes mellitus, childhood, adolescence, disability-adjusted life years, potential years of life lost, years lived with disability, Cuba

Dementia is a great challenge to public health in Cuba due to its impact on society and families. Cuba’s National Intervention Strategy for Alzheimer Disease and Dementia Syndromes is designed to address this challenge. The Strategy includes working guidelines for primary and secondary care, education about rights of people with cognitive impairment, professional development, research, and health promotion and dementia prevention. An associated action plan, focused on primary care, includes proposals for creation of memory clinics, day centers and comprehensive rehabilitation services for cognitive stimulation. Short-term measures proposed include increasing early detection; creating a dementia morbidity and mortality registry; promoting professional training; providing support for families; and promoting basic and clinical research on dementia. Medium-term proposals aim to reduce dementia incidence and mortality by controlling risk factors and promoting healthy lifestyles, offering new treatment options and optimizing early detection. A set of indicators has been developed to evaluate strategy implementation. With this strategy, Cuba joins the small number of developing countries that have responded to WHO’s call to improve care for patients with dementia and alleviate its impact on society and families.

KEYWORDS Dementia, Alzheimer disease, aging, national health programs, social stigma, primary prevention, health promotion, civil rights, Cuba

Translated and reprinted with permission from RevistaCubana de SaludPública. 2016 Apr –Jun;42(2).
Original available from: http://www.revsaludpublica.sld.cu/index.php/spu/article/view/530

The current definition of universal health coverage lacks several elements essential to advance public health. This article aims to discuss the concept and interpretation of universal health coverage and suggests an inclusive definition that is applicable to states, governments, and the societal and economic sectors ultimately responsible for public health. We will discuss the complexity and social determinants of universal health coverage, and the need for health to be built through social action, together with the states, governments and all societal actors, within a supportive legal framework. One suggestion is to consider health coverage as the ability of society, states and governments to respond to population health and well-being, which includes legislation, infrastructure availability, social capital and technology, as well as comprehensive planning, organizational, action and financing strategies to protect the health of the whole population, equally and inclusively.

KEYWORDS Universal health coverage, public health, social action, Cuba

Gestational diabetes is the most common endocrine disorder affecting pregnant women and its prevalence is on the rise. Prevalence in Cuba is about 5.8%, and global prevalence ranges from 2% to 18% depending on the criteria applied. Gestational diabetes can lead to adverse gestational outcomes, such as fetal death, preterm delivery, dystocia, perinatal asphyxia and neonatal complications. Prompt, accurate diagnosis allowing early treatment can benefit both mother and child. The disease is asymptomatic, so clinical laboratory testing plays a key role in its screening and diagnosis. Cuba’s approach to diabetes screening and diagnosis differs from some international practices. All pregnant women in Cuba are screened with a fasting plasma glucose test and diagnosed using modified WHO criteria. Some international recommendations are to skip the screening step and instead follow the diagnostic criteria of the Hyperglycemia and Adverse Pregnancy Outcomes study. In Cuba, gestational outcomes for women with diabetes (including gestational diabetes) are satisfactory (preeclampsia 5%; preterm delivery 12%; neonatal macrosomia 7.5%; congenital abnormalities 4.3% and perinatal deaths 4.8%). These data do not indicate a need to change established screening and diagnostic criteria.

KEYWORDS Gestational diabetes, screening, diagnosis, early detection, early diagnosis, Cuba

WHO considers the effects of air pollution one of the most pressing global health priorities. Several years ago, scientists began noting a link between Saharan dust (a meteorological phenomenon that diminishes air quality as it spreads over the globe) and some diseases, but the few studies to date have been inconsistent. Cuba has the human and material resources to study the association between Saharan dust and health. It is important to encourage creation of multidisciplinary research teams to do so.

KEYWORDS Health, airborne particulate matter, dust, air pollutants, environmental health, climate, Cuba

Harmful use of alcohol—the prime gateway drug to other addictions—is also a problem in Cuba, even though the National Program for Prevention of Harmful Use of Alcohol includes the most effective measures used in analogous programs around the world.

As a participant in the program’s committee and empirical observer of its accomplishments and unaccomplished goals, I draw attention to the community’s attitude of tolerance toward intoxication manifested by the lack of proportional consequences, and I insist on the need to broaden the community’s understanding of the risks of non-social drinking, which in Latin America is practically limited to alcoholism and its complications. This undervalues the damage wreaked by unpredictable and dangerous behavior under the influence, as well as the suffering of codependents and other “passive drinkers,” and the adverse effects of even social drinking.

KEYWORDS Alcohol abuse/prevention and control, alcohol consumption, alcohol drinking/culture, alcoholism, drinking behavior, behavior and behavior mechanisms, social determinants of health, social reinforcement, mass media, communication, Cuba

To encourage development of negative attitudes toward alcohol use and thus prevent early onset of alcohol use, an intersectoral intervention was conducted from 2014 to 2015 among Cuban adolescents in 14 schools in Havana. The intervention included 312 students (189 girls and 123 boys) aged 14 to 15 years in 10th grade of high school or vocational school. Workshops were conducted using participatory techniques and group dynamics. Qualitative methods were applied, including narrative, desiderative and projective techniques. Indicators included attitudes, motivation, interests and perception of risk. Following the intervention, 82.7% (258/312) of participants reported healthy cultural and recreational interests and 61.9% (193/312) reinforced negative attitudes toward drinking. Such interventions can help prevent early onset of alcohol use in school settings. Given the positive results, the intervention is slated to be reproduced in other Cuban provinces.

KEYWORDS Adolescents, prevention, alcoholism, attitudes, Cuba

Persons with disabilities constitute one of the most vulnerable groups in every society; their identification, assessment and care present a major challenge. In 2001–2003, Cuba conducted the first comprehensive national study of persons with disabilities in the Americas. In 2007–2010, the study was replicated in Bolivia, Ecuador, Nicaragua, Saint Vincent and the Grenadines, and Venezuela, at their governments’ request. Study results have enabled implementation of strategies with substancial impact on human health in these countries. In response to it, more than a million medical consultations were provided by professionals whose specialties are lacking in the participating countries, including 139,772 clinical genetic consultations. Once each country’s needs were identified, Cuba provided technical assistance with equipment supplied by Venezuela. The study led to development of public policies and programs for disability prevention and care of disabled persons in Bolivia, Ecuador, Nicaragua and Venezuela, and the opening of the National Medical Genetics Center and orthotic and prosthetic laboratories in Venezuela, and rehabilitation centers in Bolivia.

KEYWORDS Disability, epidemiology, health services research, needs assessment, human resources, workforce, Bolivia, Cuba, Ecuador, Nicaragua, Saint Vincent and the Grenadines, Venezuela

INTRODUCTION Suicide is a health problem influenced by biological, genetic, psychological, social and economic factors. It is responsible for 50% of violent deaths in the male population, worldwide, and 71% in the female. In the Americas, 65,000 deaths by suicide occur every year. It is the ninth most frequent cause of death in Cuba, and third among people aged 10–19.

OBJECTIVE Characterize the epidemiology of suicide in Cuba from 1987 to 2014.

METHODS A retrospective descriptive study was conducted. The information comprised all records of death by suicide from January 1, 1987 to December 31, 2014, in the Cuban Ministry of Public Health’s National Statistics Division database. The variables were sex, age, skin color, employment status/occupation, marital status, and method of suicide. Crude and age-standardized mortality rates and age–sex specific mortality rates were calculated, all per 100,000 population, as well as the sex ratio. Relative change over the series was calculated as a percentage. Distribution of suicides by variable was calculated and proportions expressed as percentages.

RESULTS A total of 51,113 deaths by suicide were reported (annual average 1825), of which 34,671 (67.8%) were among men. The sex ratio was 2.1:1 for the entire study period, and 3.9:1 for 2011–2014. Over the course of the period studied, age-standardized suicide rates decreased from 23.9 to 10.8 per 100,000 population (54.8% reduction). The group aged ≥60 years had the highest average age-standardized rate, 44.6 per 100,000 population. The highest suicide burden by age was in the group aged 20–59 years (60.5%). By skin color, the highest burden was in those recorded as white, 68.9%. By marital status, the highest burden was in persons with a stable partner (46.7%), and by employment status/occupation, in retired (25.9%). The most commonly used method was hanging (59.4%).

CONCLUSIONS Over the course of about three decades, suicide mortality rates have declined by almost half and they are still slightly higher than overall rates in the Americas. The most commonly used method is hanging. The sex ratio is greater than two and has increased over time. The highest rates occur in the group aged ≥60 years, but finer stratification is needed to identify an age-related risk trend. In view of Cuba’s aging population, these results are of interest for epidemiology and public health.

KEYWORDS Suicide, suicide attempt, death, mental health, Cuba

Excerpted by the author, translated and reprinted with permission from Novedades en Población. No. 7, Jul–Dec 2014;79–92. Original available from: http://www.novpob.uh.cu/index.php/rnp/article/view/219

Cuba’s accelerated trend to lower fertility and consequent contraction of population reproductive capacity have now become concerns for various social and political actors, including, of course, Cuban demographers, who have been sounding the alarm for more than three decades. The most striking characteristic of Cuba’s fertility transition is undoubtedly its abrupt onset, rapidity, and the fact that it took place in the absence of accompanying economic development. Hence the current debate focusing on the roles of the various determinants that led to the transition, and especially of economic factors at different stages, particularly in conditions of heightened population vulnerability during economic crises. This article provides elements to help fill gaps in knowledge of the fertility–development relationship today.

KEYWORDS Fertility, fertility determinants, below replacement fertility, demographic transition, population transition, development, population dynamics, Malthusianism, Cuba

Excerpted by the author, translated and reprinted with permission from Revista Cubana de Salud Pública. 2015Jan–Mar;41(1):94–114. Original available from: http://scielo.sld.cu/scielo.php?pid=S0864-34662015000100009&script=sci_arttext

This paper discusses integration and implementation of population health and social determinants approaches to the health-disease–care process in the context of ongoing changes to Cuba’s health system. Ideas for strengthening the social conceptualization of public health and prioritizing population health actions over those of individual medical care are discussed, with a view to encouraging rethinking of these as social practice. The paper aims to advance new and renewed strategic proposals for change, based on a broad view of public health and a focus on social medicine that favors a population health perspective and inclusion of a wide range of health determinants. It advances the need to develop or extend debate on the theory and social practice of epidemiology and public health while implementing needed changes in health services and medical care. The paper recommends embarking on technical discussions among all actors and protagonists, not just in the health care system but in the entire health sector, to better integrate and practice a population health approach with social determinants of health.

Intersectoral action in health refers to actions led by the health sector based on coordinated national and local policies, strategically oriented to address priority health issues where actions by other sectors can have a decisive impact on health outcomes. A Cuban example of this approach is the joint efforts by the Ministry of Public Health and the biotechnology industry in development and application of technologies for cervical cancer screening, early detection and treatment. The resulting products have been used by the National Health System since 2010, as part of efforts to reduce cervical cancer mortality. This is an example of intersectoral action intended to identify and contribute to solving problems affecting people’s well-being and quality of life.

KEYWORDS Cancer, intersectoral action, biotechnology, cervical cancer, early diagnosis, colposcopy, health technologies, Cuba

Arterial hypertension is the most prevalent non-communicable disease worldwide, and has long been recognized as a major risk factor for cardiovascular and cerebrovascular diseases. High blood pressure has deleterious consequences on the main target organs (heart, kidney, brain), and several studies have shown that brain damage is more frequent than heart and kidney involvement. Silent lesions can subsequently lead to cognitive decline, dementia or stroke.

Nevertheless, screening for subclinical brain deterioration is rarely performed because it requires imaging techniques whose scarcity and high cost rule out routine use by primary care physicians. The challenge is thus early detection of asymptomatic brain lesions with cost-effective techniques to test thousands of patients in the community. In this review we present an update on the status of biomarkers explored as alternatives for early detection of brain damage in arterial hypertension, potentially useful to identify patients needing referrals for brain MRI: ambulatory blood pressure monitoring, quantitative retinal microvascular assessment, quantitative electroencephalography, carotid ultrasonography, neurocognitive studies and blood-based biomarkers. We place special emphasis on blood-based biomarkers, for which our group reported the first preliminary evidence of an association between serum neuron-specific enolase and severity of white matter lesions in patients with essential hypertension. This review consequently explores the potential for blood-based biomarkers to provide a faster, cheaper and more accessible early-detection solution, particularly beneficial in resource-limited settings such as Cuba’s.

KEYWORDS Arterial hypertension,small vessel disease, brain damage, biomarkers, white matter diseases, leukoaraiosis, lacunar infarct, S100 calcium binding protein beta subunit, S100B protein, S100 calcium binding protein G, neuron specific enolase, NMDA receptors, receptors, N-methyl-D-aspartate, mass screening, Cuba

INTRODUCTION Cuba’s science policy is grounded in a scientific and technological innovation system applicable to all institutions. In hospitals, the system should influence medical care and administrative and teaching processes, as well as promotion of scientific activity as such.

OBJECTIVE Describe results of the Scientific and Technological Innovation System at the Dr Gustavo Aldereguía Lima University Hospital, the main provincial hospital in Cienfuegos, Cuba.

METHOD This was a key informant survey and document review concerning the hospital’s scientific activity during 2000–2014. A questionnaire was administered to 22 key informants to select key indicators and area. Data on the hospital’s scientific activity related to these indicators were retrieved from hospital, provincial public health and scientific publishing databases. A second group of 35 key informants confirmed linkages between scientific outputs and the innovation system’s main activities.

RESULTS The following were reported over the study period: sustained development of scientific human resources (40% grade II specialists, 30% master’s degree holders and 11.4% accredited academic researchers among the hospital’s professional staff), high scientific output (annual average of 445 studies completed, 118 publications and 203 projects under way) and high visibility (national and international recognition) of the hospital’s achievements in science and innovation. Key informants considered that results related to development of scientific potential were influenced by the following activities of the Scientific and Technological Innovation System: promotion of grade II specialty training, researcher accreditation and awarding of master’s degrees and PhDs in the sciences, development of an extensive continuing education program (for researchers and their mentors), public recognition of professionals with good scientific results, promotion of research and other scientific activities, and the requirement that professional and technical staff participate in national events sponsored by scientific societies.

CONCLUSIONS Implementation of a Scientific and Technological Innovation System can contribute to a hospital’s scientific capacity and productivity.

KEYWORDS Hospitals, health services research, organizational deve-lopment, organizational innovation, technology, research, science, Cuba

INTRODUCTION High prevalence of metabolic syndrome and its associated risk factors in adults represents both a Cuban and a worldwide public health problem.

OBJECTIVE Determine prevalence of metabolic syndrome’s component risk factors in a representative sample of adults in Holguín Province, Cuba.

METHODS A cross-sectional study was conducted using multistage probability sampling of four Holguín Province municipalities: Holguín, Gibara, Urbano Noris and Banes. We selected a sample of 2085 patients aged ≥20 years during 2004–2013 and measured clinical, anthropometric and biochemical variables. Risk factor prevalence rates were calculated using EPIDAT 3.1.

RESULTS Crude metabolic syndrome prevalence rate was 27.2% (CI 25.3%–29.1%). Crude prevalence rates (with 95% CI) of risk factors were as follows: hypertriglyceridemia 36.1% (34.0%–38.2%); hypercholesterolemia 25.5% (23.6%–27.4%); low HDL cholesterol 26.3% (24.4%–28.2%); high LDL cholesterol 10.1% (8.8%–11.4%); prediabetes 2.2% (1.6%–2.8%); diabetes 14.6% (13.1%–16.1%); prehypertension 3.5% (2.7%–4.3%); hypertension 34.5% (32.5%–36.5%); overweight 23.4% (21.6%–25.2%); obesity 32.0% (30.0%–34.0%) and central obesity 47.3% (45.2%–49.4%). They were significantly higher in women and older adults.

CONCLUSIONS High prevalence of risk factors associated with metabolic syndrome confirms the magnitude of this health problem, particularly in women and older adults.

KEYWORDS Metabolic syndrome, insulin resistance, hypertension, dyslipidemia, type 2 diabetes mellitus, obesity, risk factors, Cuba